Reverse Hardening
of the Arteries for
Healthy Longevity

We’re entering an era where the causes instead of symptoms of diseases are treated.

Precision medicine combined with bioengineering can reverse the process of disease formation at the root.

At Elastrin Therapeutics we’re already there.

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As we age, arteries stiffen due to calcification. It is a primary driver of heart attacks, stroke, peripheral artery disease, and limb loss, killing hundreds of millions of people globally. Every existing treatment manages the consequences. None address the cause.

Our Breakthrough

The Problem

Arteries harden with age. Currently no drug reverses it.

The Solution

Targeted reversal. Where tissue breakdown begins.

Elastrin's platform delivers therapy directly to sites of calcification, without invasive surgery or life-long drugs.

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Calcification Cleared

Average removal in treated targets.

% of Calcification removed

20%

40%

60%

80%

100%

47%

65%

Before Treatment

Week 2

Week 4

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Up to 70% reduction of calcification.

Measured in various small and large animal studies.

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A platform that enables more than one therapy.

The same targeting platform can address multiple cardiovascular and age-related conditions , making Elastrin a scalable system, not a one-off asset.

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Anchored by Leading Institutions.

Elastrin's science and development are supported by collaborations with NIH, Clemson University, BIO, and additional academic and translational partners.

What leaders in the field are saying.

Dr. Francis Collins

Former Director, U.S. National Institutes of Health (2009–2021)

"Using these nanoparticles may enable medical treatment without requiring surgical interventions. Fixing the vessels may ultimately reverse the course of the disease."

Dr. Fahad Shuja, MD

Vascular Surgeon at Mayo Clinic in Minnesota

"Untreated PAD's biggest risk is limb loss, which causes loss of independence. What limb loss means for patients is unimaginable — one of the most life-changing moments for that patient."

Company

Science

Platform

Investors

News & Events

Elastrin Presents at MedTech Ahead 2025

Elastrin Presents at MedTech - Elastrin made a strong impression at MedTech Ahead 2025 by presenting its latest advancements in medical technology.

Elastin: The rubber band of life

You may recognize elastin as a key ingredient in youthful skin, but did you know it’s also an essential component of your heart, lungs, and blood vessels? Recent advances in elastin preservation and regeneration research are unlocking promising pathways toward improved tissue health and longevity. Dr. Narendra Vyavahare is at the forefront of this exciting field. With a distinguished career focused on heart valve biomaterials, site-specific therapies, and extracellular matrix remodeling, Dr....

#1 Bestseller features Elastrin scientist’s discoveries & inventions

May 2024 - #1 Amazon bestseller status has been awarded to an Elastrin co-founder's book Discovering the Nature of Longevity: Restoring the heart and body by targeting hidden stress . Douglas Mulhall's book is the first to reveal for a general audience the mysteries of elastin, along with the groundbreaking discoveries by Elastrin's CSO Dr. Naren Vyavahare. The book also chronicles co-invention by Dr. Charles Rice and Dr. Vyavahare of an antibody specific for damaged elastin fiber. It...

Reverse Hardening of the Arteries for Healthy Longevity